Bayan Fage: Haɓaka fibrin mai-arziƙin platelet (PRF) ya sauƙaƙa sosai da tsarin shirye-shiryen abubuwan da ke tattare da kwayoyin halitta, kamar plasma mai arzikin platelet (PRP), kuma ya sauƙaƙe aikace-aikacen su na asibiti.An nuna tasirin aikin PRF sau da yawa a cikin binciken farko da na asibiti;duk da haka, har yanzu yana da rigima ko abubuwan haɓaka sun fi mayar da hankali sosai a cikin shirye-shiryen PRF don sauƙaƙe warkar da rauni da farfadowa na nama.Don magance wannan al'amari, mun yi nazarin kwatancen abubuwan da ke cikin abubuwan haɓakawa a cikin PRP da abubuwan da suka samo asali, kamar su ci-gaba PRF (A-PRF) da abubuwan haɓaka haɓaka (CGF).
Hanyoyi: An shirya PRP da abubuwan da suka samo asali daga samfuran jini iri ɗaya waɗanda aka tattara daga masu ba da gudummawa lafiya.Shirye-shiryen A-PRF da CGF sun kasance masu kama da juna kuma an ba da su don samar da ruwan 'ya'ya.Platelet da fararen ƙwayoyin jini a cikin shirye-shiryen A-PRF da CGF an ƙaddara su ta hanyar cire waɗannan ƙididdiga a cikin juzu'in jan jini, juzu'ai na acellular serum, da ɓangarorin cirewar A-PRF/CGF daga waɗannan ƙididdiga na samfuran jini duka.Matsakaicin abubuwan haɓakawa (TGF-β1, PDGF-BB, VEGF) da cytokines pro-inflammatory (IL-1β, IL-6) an ƙaddara ta amfani da kayan aikin ELISA.
Sakamako: Idan aka kwatanta da shirye-shiryen PRP, duka abubuwan A-PRF da CGF sun ƙunshi matakan dacewa ko mafi girma na platelet da abubuwan haɓakar platelet.A cikin gwajin haɓakar ƙwayoyin cuta, duka abubuwan A-PRF da CGF sun haɓaka haɓakar ƙwayoyin periosteal na ɗan adam ba tare da raguwa mai yawa ba a mafi girma allurai.
Ƙarshe: Waɗannan bayanai sun nuna a fili cewa duka shirye-shiryen A-PRF da CGF sun ƙunshi nau'ikan abubuwan haɓaka masu girma waɗanda ke iya haɓaka haɓakar ƙwayoyin periosteal, suna ba da shawarar cewa shirye-shiryen A-PRF da CGF suna aiki ba kawai azaman kayan ɓata ba amma har ma a matsayin tafki don isar da wasu. abubuwan girma a wurin aikace-aikacen.
Mahimman kalmomi: Girman girma, Platelet-rich plasma, Platelet-rich fibrin, Plasma mai arziki a cikin abubuwan haɓaka, Abubuwan haɓaka haɓakar haɓaka: ACD, Acid citrate dextrose bayani;ANOVA, Binciken bambance-bambance;A-PRF, Babban fibrin mai wadataccen platelet;A-PRFext, A-PRF tsantsa;CGF, Abubuwan haɓaka haɓaka haɓaka;CGFext, CGF tsantsa;ELISA, Enzyme-linked immunosorbent assay;IL-1β, Interleukin-1β;IL-6, Interleukin-6;PDGF-BB, Platelet-wanda aka samu girma factor-BB;Platelet, PLT;PRGF, Plasma mai arziki a cikin abubuwan haɓaka;PRP, Platelet mai wadatar plasma;RBC, Ruwa.
Lokacin aikawa: Oktoba-12-2022