PRP Tubes Acd Tubes
Takaitaccen Bayani:
Maganin Citrate Dextrose na Anticoagulant, wanda aka fi sani da ACD-A ko Magani A ba shi da pyrogenic, maganin bakararre.Ana amfani da wannan sinadari azaman maganin hana jini a cikin samar da plasma mai arzikin platelet (PRP) tare da Tsarin PRP don sarrafa jini na waje.
Maganin Citrate Dextrose na Anticoagulant, wanda aka fi sani da ACD-A ko Magani A ba shi da pyrogenic, maganin bakararre.Ana amfani da wannan sinadari azaman maganin hana jini a cikin samar da plasma mai arzikin platelet (PRP) tare da Tsarin PRP don sarrafa jini na waje.Magungunan rigakafi waɗanda ke tushen citrate suna amfani da ikon citrate ion don chelate ionized calcium wanda ke cikin jini don hana coagulation na jini kuma ya samar da hadadden calcium-citrate wanda ba ionized.
Samfurin maganin ƙwanƙwasa guda ɗaya wanda Hukumar Abinci da Magunguna ta Amurka ta amince da a yi amfani da ita don shirya PRP a cikin Tsarin PRP daban-daban shine ACD-A.Dangane da binciken da aka gudanar a cikin 2016 akan PRP da aka samu tare da magunguna daban-daban da tasirin su akan halayen ƙwayoyin stromal mesenchymal a cikin vitro da lambobin platelet, akwai sakamako masu kyau a cikin amfani da PRP don gyaran nama na musculoskeletal.
Don ware platelets ana ba da shawarar maye gurbin daidaitaccen sodium citrate na Acid Citrate Dextrose (ACD-A) kamar yadda hanyar keɓewa na buƙatar matakan wankewa da yawa.Platelets sun fi kwanciyar hankali a 37C yayin juyawa, amma juyar da su a cikin zafin jiki (25 C) shima yana aiki lafiya.Rage pH ta hanyar ACD-A (yana zuwa kusa da 6.5) yana taimakawa wajen rage kunna tasirin thrombin a cikin bututun platelet, kuma yana ba da gudummawa ga ci gaba da kiyaye tsarin halittar platelet yayin da yake canza aiki zuwa ƙaramin.Yawanci kuna buƙatar sake dakatar da platelets zuwa madaidaicin Tyrode Buffer (pH 7.4) don dawo da aikinsu.ACD yana da fa'idodi da yawa idan ana maganar adana platelet
Lokacin da aka yi amfani da ACD, sakamakon ya nuna yawan adadin platelet a cikin jini gaba ɗaya.Duk da haka, amfani da EDTA ya kuma ƙarfafa girma a cikin ma'auni na platelet bayan an aiwatar da matakan centrifugation na jini don samun PRP.Bayan haka, yin amfani da ACD ya haifar da haɓakar ƙwayoyin stromal mesenchymal.Sabili da haka, an ƙaddamar da cewa magungunan rigakafi ciki har da ACD-A suna taka muhimmiyar rawa a cikin shirye-shiryen PRP kuma suna taimakawa wajen inganta tsarin da yawa.
